PROXIMAL DISCREPANCY IN INTRINSIC ATOMIC INTERACTION ARRESTS G2/M PHASE BY INHIBITING CYCLIN B1/CDK1 TO INFER MOLECULAR AND CELLULAR BIOCOMPATIBILITY OF D-LIMONENE

Abstract The quest for different natural compounds for different biomedical applications especially in the treatment of cancer is Guide Rail at a high pace with increasing incidence of severity.d-limonene has been portrayed as one of the effective potential candidate centered to the context of breast cancer.The anticipation of its count as an effec

Targeted therapies are the state of the art in oncology today, and every year new Tumor-associated antigens (TAAs) are developed for preclinical research and clinical trials, but few of them really change the therapeutic scenario.Difficulties, either to find antigens that are T-Shirts solely expressed in tumors or the generation of good binders to

Abstract The microenvironment of immunosuppression and low immunogenicity of tumor cells has led to unsatisfactory therapeutic effects of the currently developed nanoplatforms.Immunogenic cell death, such as pyroptosis and ferroptosis, can efficiently boost antitumor immunity.However, the exploration of nanoplatform for dual function Feeders induce

Archaeologists commonly use Hat Bands subjective classifications to group ceramic vessels into different classes, but the usefulness of such tools for creating narratives about the past is seldom questioned.After noticing that certain ceramic classes from the Bronze Age necropolis of Mokrin have quite similar shape and size, we decided to undertake

Topic models extract latent concepts from texts in the form of topics.Lifelong topic models extend topic models by learning topics continuously based on accumulated knowledge from the past which is updated continuously as new information becomes available.Hierarchical topic modeling extends topic modeling by extracting topics and organizing them in